How do you administer a Berinert?
Administer Berinert at a dose of 20 International Units (IU) per kg body weight by intravenous injection. Doses lower than 20 IU/kg body weight should not be administered. Berinert is provided as a freeze-dried powder for reconstitution with the Sterile Water for Injection, USP provided.
How do you administer a C1 esterase inhibitor?
CINRYZE ® (C1 esterase inhibitor [human]) is administered by intravenous (or IV) injection, meaning it is injected into a vein in the arm. You can choose to have your injection administered by a healthcare provider or caregiver, or a healthcare provider can show you how to give it to yourself.
How long does it take Berinert to work?
BERINERT provides fast onset of relief from HAE attacks in as little as: 15 minutes for laryngeal attacks. The time to complete resolution of symptoms was 8.4 hours. 48 minutes for abdominal and facial attacks.
When was berinert FDA approved?
Development Timeline for Berinert
| Date | Article |
|---|---|
| Oct 12, 2009 | Approval CSL Behring Announces FDA Approval of Berinert, First and Only Therapy Approved for the Treatment of Acute Abdominal and Facial Attacks of Hereditary Angioedema in U.S. |
How do you treat hereditary angioedema?
Medicines called danazol and oxandrolone can help reduce the chances of swelling occurring if you have hereditary angioedema. These medicines boost the levels of C1 esterase inhibitor in your blood. Low levels of this substance are what causes the swelling.
Can kalbitor be self administered?
No, you shouldn’t self-inject Kalbitor. Kalbitor can cause a serious allergic reaction called anaphylaxis. * So only a healthcare professional should give you the injections. In fact, you’ll need to receive them in a medical setting where anaphylaxis and hereditary angioedema (HAE) can be treated.
How is BERINERT stored?
BERINERT is provided as a freeze-dried powder for reconstitution with the Sterile Water for Injection, USP provided. Store the vial in the original carton in order to protect from light. Do not freeze. Check the expiration date on the product vial label and on the administration kit.
How is BERINERT made?
BERINERT is made from human blood. BERINERT and the human plasma from which it’s made have been carefully processed and screened to remove or inactivate known viruses.
What is Berinert made of?
Berinert is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease.
What company makes berinert?
CSL Behring—Committed to patients with HAE and the healthcare professionals who treat them. CSL Behring, the maker of BERINERT, is a world leader in specialty biopharmaceuticals and is committed to people around the world with rare and serious conditions like HAE.
