What are examples of nephrotoxic drugs?

The nephrotoxic effects of cyclosporine, aminoglycoside antibiotics, cisplatin, amphotericin B, beta-lactam antibiotics and indomethacin are reviewed. These drugs were chosen because they are among the most frequent causes of renal injury in children. In addition, their nephrotoxicity is caused by different mechanisms.

What foods are nephrotoxic?

Restrictions and foods to avoid on a nephrotic syndrome diet

  • processed cheeses.
  • high-sodium meats (bologna, ham, bacon, sausage, hot dogs)
  • frozen dinners and entrées.
  • canned meats.
  • pickled vegetables.
  • salted potato chips, popcorn, and nuts.
  • salted bread.

Are antibiotics nephrotoxic?

The potentially nephrotoxic antibiotics in current clinical use are neomycin, kanamycin, paromomycin, bacitracin, the polymyxins (polymyxin B, and colistin), and amphotericin B. Nephrotoxicity was reported with early lots of streptomycin, but the drug now commercially available does not appear to have this property.

Is ciprofloxacin nephrotoxic?

Nephrotoxic reactions to ciprofloxacin appear to be unusual but potentially serious. It has previously been reported that fluoroquinolones could cause acute renal failure (ARF) after the ingestion of large quantities, but it is now recognized that therapeutic doses of fluoroquinolones can also cause renal injury.

Is omeprazole nephrotoxic?

INTRODUCTION AND AIMS: Omeprazole is a proton pump inhibitor (PPI) for patients with gastroesophageal reflux and peptic ulcer. It was not considered nephrotoxic, but recent case reports and epidemiological studies suggest a paradigm change.

Is tomato bad for kidney?

Tomatoes are another high potassium fruit that should likely be limited on a renal diet.

How bad is omeprazole for kidneys?

In recent years, the use of proton pump inhibitors (PPI), especially omeprazole, has been associated with development of chronic kidney disease (CKD). These drugs are widely used worldwide. Although some studies have found an association between the use of PPI and the onset of acute renal failure and CKD.

Which is the best definition of nephrotoxicity?

The epidemiology of drug-induced nephrotoxicity is currently based on literature focusing on acute kidney injury (sudden episode of kidney failure or kidney damage that happens within a few hours or a few days).

Are there any drugs that are inherently nephrotoxic?


Is there a blood test for nephrotoxicity?

Nephrotoxicity should not be confused with the fact that some medications have a predominantly renal excretion and need their dose adjusted for the decreased renal function (e.g. heparin). Nephrotoxicity is usually monitored through a simple blood test. An elevated level of creatinine indicates poor renal function.

Can a drug induced nephrotoxicity be reversible?

Monitor renal function and vital signs after starting or increasing the dose of drugs associated with nephrotoxicity, especially when used chronically. Drug-induced renal impairment is generally reversible, provided the nephrotoxicity is recognized early and the offending medication is discontinued.