What are the symptoms of molybdenum deficiency?
Symptoms were tachycardia, tachypnea, headache, nausea, vomiting, and coma. Laboratory tests showed high levels of sulfite and xanthine and low levels of sulfate and uric acid in the blood and urine.
How do you test for molybdenum cofactor deficiency?
Diagnostic laboratory testing for both molybdenum cofactor deficiency (MCD) and isolated sulfite oxidase deficiency involves urine analysis for S-sulfocysteine. The finding of low or nondetectable serum uric acid levels may suggest the diagnosis of MCD but is not always a reliable indicator.
What is MoCD?
Molybdenum cofactor deficiency (MoCD) is a rare metabolic disorder characterized by severe and rapidly progressive neurologic damage caused by the functional loss of sulfite oxidase, 1 of 4 molybdenum-dependent enzymes.
What is MoCD type A?
Molybdenum cofactor deficiency (MoCD) Type A is a rare genetic disease (a specific kind, also called an inborn error of metabolism) that can appear shortly after birth. 1,2. Children with MoCD Type A appear normal when born.
How do you fix molybdenum deficiency?
Molybdenum is more likely to be deficient in acid soils. Liming to bring pH above 5.5 usually fixes molybdenum deficiency in the long term. Applying a molybdenum fertiliser can correct molybdenum deficiency symptoms in plants more quickly.
How do you increase molybdenum?
Legumes are the richest sources of molybdenum [16]. Other foods high in molybdenum include whole grains, nuts, and beef liver [1,14,17,18]. The top sources of molybdenum in U.S. diets are legumes, cereal grains, leafy vegetables, beef liver, and milk [17].
What causes molybdenum deficiency?
Molybdenum cofactor deficiency is caused by mutations in the MOCS1, MOCS2, or GPHN gene. There are three forms of the disorder, named types A, B, and C (or complementation groups A, B, and C).
What is molybdenum supplement?
What is molybdenum and what does it do? Molybdenum is a mineral that you need to stay healthy. Your body uses molybdenum to process proteins and genetic material like DNA. Molybdenum also helps break down drugs and toxic substances that enter the body.
What is molybdenum deficiency?
Molybdenum cofactor deficiency is a rare condition characterized by brain dysfunction (encephalopathy) that worsens over time. Babies with this condition appear normal at birth, but within a week they have difficulty feeding and develop seizures that do not improve with treatment (intractable seizures).
What happens if you have too little molybdenum?
Molybdenum deficiency is very rare in the United States. It happens only in people with a very rare genetic disorder called molybdenum cofactor deficiency. This disorder prevents the body from using molybdenum. It can cause seizures and severe brain damage that usually leads to death within days after birth.
How can I get molybdenum naturally?
There is very little data on the specific molybdenum content of certain foods, as it depends on the content of the soil. Although amounts vary, the richest sources are usually beans, lentils, grains and organ meats, particularly liver and kidney.
