What drug class is EPOGEN?
Epoetin alfa belongs to a class of drugs called colony-stimulating factors because of their ability to stimulate cells in the bone marrow to multiply and form colonies of identical cells.
What is the purpose of EPOGEN?
EPOGEN® increases hemoglobin (Hb) levels and decreases the need for blood transfusions. Your doctor will determine the appropriate Hb level for you to reduce the need for blood transfusions. EPOGEN® should not be used in place of emergency red blood cell transfusions to treat anemia.
What is the mechanism of action for epoetin?
Erythropoietin binds to specific receptors (JAK-STAT-binding receptor) on the surface of its target cells. It subsequently alters the phosphorylation of intracellular proteins and activates transcription factors to regulate gene expression.
Is EPOGEN only for dialysis patients?
Epogen is indicated for the treatment of anemia due to chronic kidney disease (CKD), including patients on dialysis and not on dialysis to decrease the need for red blood cell (RBC) transfusion.
What drug classification is Plaquenil?
It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis.
Is Epogen a Part B drug?
Do Medicare prescription drug plans cover Epogen? No. In general, Medicare prescription drug plans (Part D) do not cover this drug.
What is the difference between Epogen and Aranesp?
There are no clinically significant differences in the safety and efficacy of epoetin alfa (Epogen, Procrit) and darbepoetin alfa (Aranesp), the two drugs most commonly used to treat anemia in cancer patients undergoing chemotherapy or radiation treatments, according to a new report by the Agency for Healthcare …
Can Epogen be given at home?
Use these Instructions for Use if you or your caregiver has been trained to give Epogen injections at home. Do not give yourself the injection unless you have received training from your healthcare provider. If you are not sure about giving the injection or you have questions, ask your healthcare provider for help.
Can Epogen be given IV push?
Epogen can be injected in your vein through a special access port placed by your healthcare provider. This type of Epogen injection is called an intravenous (IV) injection. This route is usually for hemodialysis patients.
How is Epogen supplied?
Epogen (epoetin alfa) injection for intravenous or subcutaneous administration is formulated as a sterile, clear, colorless liquid in vials in multiple formulations. Single-dose vials, formulated with an isotonic sodium chloride/sodium citrate-buffered solution, are supplied in multiple strengths.
Is EPOGEN given IM or SQ?
Epogen can be injected directly into a layer of fat under your skin. This is called a subcutaneous injection. When giving subcutaneous injections, follow your healthcare provider’s instructions about changing the site for each injection.
Does EPOGEN affect your kidneys?
Epoetin alfa may sometimes cause or worsen high blood pressure, especially in patients with long-term kidney failure. This effect may be caused by the number of red blood cells increasing too quickly, usually within the first 3 months of starting treatment.
What’s the generic name for the drug Epogen?
Epogen. Generic Name: epoetin alfa (e POE e tin AL fa) Brand Name: Epogen, Procrit, Retacrit. Medically reviewed by Sophia Entringer, PharmD. Last updated on May 28, 2020. Uses. Warnings. Dosage.
Are there any side effects to taking Epogen?
Medically reviewed on Aug 10, 2018. Epogen (epoetin alfa) is a man-made form of a protein that helps your body produce red blood cells. This protein may be reduced when you have kidney failure or use certain medications. When fewer red blood cells are produced, you can develop a condition called anemia.
What kind of protein is Epogen Alfa made of?
Epogen (epoetin alfa) is a man-made form of a protein that helps your body produce red blood cells.
What kind of anemia can Epogen be used for?
Epogen is used to treat anemia caused by chemotherapy or chronic kidney disease, anemia caused by taking zidovudine to treat HIV (human immunodeficiency virus), or anemia due to other reasons. Epogen is also used to reduce the need for red blood cell transfusions in people having certain types of surgery.