What is CYP19A1 gene?

The CYP19A1 gene provides instructions for making an enzyme called aromatase. This enzyme converts a class of hormones called androgens, which are involved in male sexual development, to different forms of the female sex hormone estrogen.

What converts testosterone to estradiol?

Estrogens are generated mainly by the action of aromatase, which converts testosterone to estradiol and androstenedione to estrone.

How do you know if you have aromatase deficiency?

In adulthood, symptoms include virilisation, absent of breast development, primary amenorrhea and infertility, and multicystic ovaries. Other symptoms include hypergonadotropic hypogonadism, polycystic ovaries, hypoplastic ovaries and tall stature.

Does estrogen increase with testosterone?

But estrogen needs to stay in balance with testosterone to help control sex drive, the ability to have an erection, and the production of sperm. Testosterone naturally decreases as men age, while estrogen increases.

What are the long term side effects of aromatase inhibitors?

Aromatase inhibitors tend to cause fewer serious side effects than tamoxifen, such as blood clots, stroke, and endometrial cancer. But aromatase inhibitors can cause more heart problems, more bone loss (osteoporosis), and more broken bones than tamoxifen, at least for the first few years of treatment.

Do eggs raise estrogen levels?

Products like eggs or milk contain high estrogen levels because they are produced in parts of the animal’s body that regulate its hormones. Eating high estrogen foods can help people who suffer from various conditions related to low estrogen levels.