What is febuxostat Atenurix used for?
Febuxostat is in a class of medications called xanthine oxidase inhibitors. It works by decreasing the amount of uric acid that is made in the body. Febuxostat is used to prevent gout attacks but not to treat them once they occur.
Is febuxostat stronger than allopurinol?
Research shows febuxostat is more effective than allopurinol in reducing serum urate levels in patients with gout. Research shows febuxostat is more effective than allopurinol in reducing serum urate levels in patients with gout.
What drug can replace allopurinol?
Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase, is a potential alternative to allopurinol for patients with hyperuricemia and gout.
Does febuxostat affect liver?
No instances of acute liver failure or chronic liver injury have been reported due to febuxostat, but the clinical experience with this agent is limited.
Is febuxostat bad for kidney?
Febuxostat has shown to be safe and effective in patients with moderate to severe renal impairment, and dose adjustment is not required in these patients.
Is febuxostat bad for the heart?
Compared with other SU-lowering treatments, febuxostat does not increase or decrease the risk of cardiovascular disease but may increase the risk of CVD death. More RCTs measuring cardiovascular safety as a primary outcome are needed to adequately evaluate the risk of CVD with febuxostat.
Is febuxostat good for kidney?
Does febuxostat cause death?
Use of febuxostat is not associated with increased risk for all-cause mortality, death from cardiovascular diseases (CVD), or CVD events, according to study results published in The Journal of Rheumatology.
Does febuxostat reduce creatinine?
Although febuxostat group showed significantly decreased serum creatinine level, the absolute value of this decrease was small (0.03 mg/dL). Considering that the study duration was only 4 weeks, more sustained suppression might have led to further change.