What is Fenethylline used for?

Fenethylline was used as medicament for hyperactivity disorders in children, narcolepsy and depression, but it has also been used as a drug of abuse under the common name of ‘captagon’.

Is selegiline a stimulant?

It belongs to a class of drugs known as stimulants. Selegiline is used to treat Parkinson’s disease-induced movement disorders. This combination drug is used for the treatment of ADHD, and attention deficit hyperactivity disorder.

How is selegiline metabolized?

Selegiline is mostly metabolized in the intestines and liver; it and its metabolites are excreted in the urine. Buccal administration of selegiline results in 5-fold higher bioavailability, more reproducible blood concentration, and produces less amphetamine metabolites than the oral tablet form.

Why Captagon is banned?

In April 2020, Saudi Arabia seized 44.7 million Captagon pills smuggled from Syria, and imposed an import ban on fruits and vegetables from Lebanon citing drug smuggling concerns, causing the price of Lebanese lettuce to plummet.

Does selegiline help anxiety?

These results indicate that selegiline has antidepressant and mild anxiolytic effects in CD157 KO mice, and suggest that it is an effective antiparkinsonian drug for depressive and anxiety symptoms in PD patients with a CD157 single nucleotide polymorphism (SNP).

Is selegiline an irreversible MAOI?

Selegiline, an irreversible and selective inhibitor of monoamine oxidase type B (MAO-B), is metabolized into desmethylselegiline, levomethamphetamine, and levoamphetamine.

Is selegiline a dopamine agonist?

Selegiline Hydrochloride Dopamine agonist. Selegiline has been known by many names. Selegiline hydrochloride is the official United States Pharmacopeia (USP) drug name, but most clinicians know it by the older name, l-deprenyl. (l-deprenyl is distinguished from its steroisomer d-deprenyl.)

How bad is Captagon?

Captagon is an addictive drug that fuels conflicts in the Middle East4. Fighters on Captagon or Amphetamines may feel a sense of well-being, euphoria and invincibility. It is clear that these drugs are favored to suppress pain and increase aggression in soldiers.