What is PhSNa?

PhSNa- phenyl and sodium attached to sulphur.

How is thiophenol made?

Thiophenol can be manufactured from chlorobenzene and hydrogen sulfide over alumina at 700 to 1,300 °F (371 to 704 °C). The disulfide is the primary byproduct. The reaction medium is corrosive and requires ceramic or similar reactor lining. Aryl iodides and sulfur in certain conditions may also produce thiophenols.

Why is thiophenol more acidic?

Since sulfur is larger than oxygen and has a larger electron cloud to stabilize a negative charge, it has a more stable conjugate base and thus should be the stronger acid. However, according to PubChem, pKa=4.82 for butyric acid, and pKa=6.62 for thiophenol.

Why thiols are called mercaptans?

Thiols are sometimes referred to as mercaptans. The term “mercaptan” /mərˈkæptæn/ was introduced in 1832 by William Christopher Zeise and is derived from the Latin mercurio captāns (capturing mercury) because the thiolate group (RS−) bonds very strongly with mercury compounds.

What is sodium Thiophenolate?

Sodium thiophenolate has been used for the synthesis of MCoTI-I and MCoTI-II cyclotides, which are naturally-occurring cyclic cystine-knot microprotein trypsin inhibitors. It may be employed in the following studies: Synthesis of Et4N+ salts of homoleptic arylthiolate Ti(IV) complex, [Ti(SPh)6]2-.

What is the conjugate base of thiophenol?

Thiolate
Thiolate: The conjugate base of a thiol. Contains a sulfur atom with three lone pairs and a negative formal charge. Deprotonation of thiophenol with a NaOH (a strong base) gives thiophenolate a thiolate), the conjugate base of thiophenol.

Does thiol act as a base?

Thiols are easily deprotonated. Relative to the alcohols, thiols are more acidic. The conjugate base of a thiol is called a thiolate.

What is the redox reaction of thiophenol base?

Thiophenols, especially in the presence of base are easily oxidized to diphenyl disulfide : The disulfide can be reduced back the thiol using sodium borohydride followed by acidification. This redox reaction is also exploited in the use of C 6 H 5 SH as a source of H atoms.

What is the formula for thiophenol in water?

Thiophenol is an organosulfur compound with the formula C 6 H 5 SH, sometimes abbreviated as PhSH. This foul-smelling colorless liquid is the simplest aromatic thiol.

How is thiophenol produced in a nuclear reactor?

Thiophenol can be manufactured from chlorobenzene and hydrogen sulfide over alumina at 700 to 1,300 °F (371 to 704 °C). The disulfide is the primary byproduct. The reaction medium is corrosive and requires ceramic or similar reactor lining. Aryl iodides and sulfur in certain conditions may also produce thiophenols.

How is a phenol converted to a thiophenol?

Via the Newman–Kwart rearrangement, phenols ( 1) can be converted to the thiophenols ( 5) by conversion to the O-aryl dialkylthiocarbamates ( 3 ), followed by heating to give the isomeric S -aryl derivative ( 4 ).