What is the typical cause of death that is associated with Marfan syndrome?

Cardiovascular complications develop throughout life, particularly aortic pathology, the major cause of death in MFS.

What is the most life threatening aspect to a person with Marfan syndrome?

Cardiovascular complications The most dangerous complications of Marfan syndrome involve the heart and blood vessels. Faulty connective tissue can weaken the aorta — the large artery that arises from the heart and supplies blood to the body. Aortic aneurysm.

Is Marfan a terminal?

How often is the condition fatal? Marfan’s disease used to always be fatal—a person wouldn’t normally live past the age of 45. Today, with aggressive treatment, people can live well beyond that. One of the difficulties is that in patients with Marfan’s disease you tend to chase the aorta.

How long is the average lifespan of someone with Marfan syndrome?

One in 10 patients may have a high risk of death with this syndrome due to heart problems. Despite the high risk for Marfan related cardiovascular problems, the average life expectancy of those with Marfan syndrome is nearly 70 years. The life expectancy in this syndrome has increased to greater than 25% since 1972.

Does Marfan syndrome get worse with age?

Marfan syndrome can be mild to severe, and may become worse with age, depending on which area is affected and to what degree. In Marfan syndrome, the heart is often affected. The aorta, the major artery of the body, may be more dilated (widened) than average.

What is the average lifespan of someone with Marfan syndrome?

What is Marfan syndrome life expectancy?

The mean life expectancy for untreated patients with Marfan syndrome is 32 years with aortic dissection, aortic rupture or cardiac failure due to mitral and aortic valve regurgitation as the predominant cause of death in > 90% of the cases.

What is the life expectancy of someone with Marfan?

How is the family of a person with Marfan syndrome affected?

In about 3 out of 4 cases, the gene is inherited from a parent who is affected. Each child of an affected parent has a 1 in 2 chance of having the disorder (autosomal dominant inheritance). In about 1 out of 4 cases, the abnormal gene is from a new mutation.

What is the lifespan of a person with Marfan syndrome?

How does Marfan syndrome affect the human body?

What is Marfan syndrome? Marfan syndrome is a genetic condition that affects connective tissue, which provides support for the body and organs. Marfan syndrome can damage the blood vessels, heart, eyes, skin, lungs, and the bones of the hips, spine, feet, and rib cage.

What should your arm span be for Marfan syndrome?

Typically, a person’s arm span should be less than their body height; an increased arm span to body height ratio of >1.05 is considered a positive sign for Marfan syndrome. Using the Wrist Sign and/or Thumb Sign is also another quick screen which can be used in clinic.

Is there a cure or treatment for Marfan syndrome?

Marfan syndrome has no cure. However, treatments can help delay or prevent complications, especially when started early. Marfan syndrome can affect many parts of your body, including your heart, bones and joints, eyes, nervous system, and lungs. The type of treatment you receive will depend on your signs and symptoms.

What happens to the mitral valve with Marfan syndrome?

Marfan syndrome also can cause problems with the heart’s mitral (MI-trul) valve. This valve controls blood flow between the upper and lower chambers on the left side of the heart. Marfan syndrome can lead to mitral valve prolapse (MVP).