What is the use of Phenobarbitone tablets?

Phenobarbital is a barbiturate (bar-BIT-chur-ate). Phenobarbital slows the activity of your brain and nervous system. Phenobarbital is used to treat or prevent seizures. Phenobarbital is also used short-term as a sedative to help you relax.

What is phenobarbital used for in humans?

Phenobarbital is used to control seizures. Phenobarbital is also used to relieve anxiety. It is also used to prevent withdrawal symptoms in people who are dependent (‘addicted’; feel a need to continue taking the medication) on another barbiturate medication and are going to stop taking the medication.

Is phenobarbital used for sleep?

Phenobarbital belongs to the class of medications called barbiturates. It is used to treat insomnia (difficulty sleeping) and as a sedative to relieve the symptoms of anxiety or tension.

Does phenobarbital lower blood pressure?

At anticonvulsant dosage, phenobarbital sodium decreased mean arterial blood pressure transiently during steady state and significantly reduced total cerebral blood flow during phenylephrine-induced hypertension without reducing mean arterial blood pressure.

Is phenobarbital given IM?

Phenobarbital sodium may be administered intramuscularly or intravenously as an anticonvulsant for emergency use. When administered intravenously, it may require 15 or more minutes before reaching peak concentrations in the brain.

Why is phenobarbital given at night?

Phenobarbital is usually taken just once a day. Most people find that sleepiness is less of a problem during the day if they take the phenobarbital 30 to 60 minutes before bedtime.

Is the phenobarbital in sodium a narcotic?

It is an organic sodium salt and a member of barbiturates. It contains a phenobarbital. Sodium phenobarbital is an odorless white crystalline powder. Aqueous solutions are alkaline to litmus and phenolphthalein (pH approximately 9.3). Bitter taste. A narcotic. sodium;5-ethyl-4,6-dioxo-5-phenyl-1 H -pyrimidin-2-olate

Which is better for seizures phenytoin or phenobarbital?

Phenobarbital is used in the treatment of all types of seizures, except absence seizures. It is no less effective at seizure control than phenytoin, however phenobarbital is not as well tolerated. Phenobarbital may provide a clinical advantage over carbamazepine for treating partial onset seizures.

What happens when phenobarbitone is in high concentrations?

At high concentrations Phenobarbitone directly increases chloride ion conductance and decreases transmission of calcium ion (Ca2+ ) dependent neurotransmitters. Phenobarbitone also inhibits excitatory glutamate neurotransmitters. At high concentration it also inhibits sodium ion channel and potassium ion channel.

How is phenobarbital used in the developing world?

The World Health Organization (WHO) gives phenobarbital a first-line recommendation in the developing world and it is commonly used there. Phenobarbital is the first-line choice for the treatment of neonatal seizures. Concerns that neonatal seizures in themselves could be harmful make most physicians treat them aggressively.