What is type 2 neurofibromatosis?
Neurofibromatosis type 2 (NF2) is a genetic condition that causes tumours to grow along your nerves. The tumours are usually non-cancerous (benign) but may cause a range of symptoms. Neurofibromatosis type 1 (NF1) is covered separately because it has different symptoms and causes.
What is the characteristic feature of neurofibromatosis type II?
Neurofibromatosis 2 (NF2) is a rare genetic disorder that is primarily characterized by noncancerous (benign) tumors of the nerves that transmit balance and sound impulses from the inner ears to the brain (bilateral acoustic neuromas/vestibular schwannomas).
What are the 3 types of neurofibromatosis?
These tumors can develop anywhere in the nervous system, including the brain, spinal cord and nerves. There are three types of neurofibromatosis: neurofibromatosis 1 (NF1), neurofibromatosis 2 (NF2) and schwannomatosis.
Is neurofibromatosis type 2 common?
How common is NF2? It is estimated that about 1 in 40,000 people has NF2. About 50% of people affected by NF2 do not have any family history of the condition. They have a de novo (new) mutation in the NF2 gene.
What is the NF2 gene?
Neurofibromatosis type 2 (NF2) is a genetic disorder that involves changes in the NF2 gene. This particular gene helps in the production of merlin (also called schwannomin), a protein that stops tumors from forming. The gene is located on chromosome 22.
How is neurofibromatosis type 2 diagnosed?
How is neurofibromatosis type 2 (NF2) diagnosed?
- Magnetic resonance imaging (MRI) scan of the brain and spinal cord to determine the location of the tumors.
- Hearing tests.
- Vision tests.
- Genetic testing.
Which type of neurofibromatosis is most common?
Neurofibromatosis 1 (NF1) is the most common of the three conditions. Although many people with NF1 inherit the gene that causes the condition, between 30 and 50 percent of cases arise from a spontaneous genetic mutation in the NF1 gene.
How long do people with NF2 live?
Tumours that develop inside the brain and spinal cord can place a strain on the body and shorten life expectancy. The average life expectancy for someone with NF2 is 65 years of age.
How do you know if you have NF2?
Early symptoms of NF2 include: Problems with balance (such as dizziness). Problems with hearing. Ringing in the ears, also called tinnitus.
Is neurofibromatosis life threatening?
In most cases, symptoms of NF1 are relatively mild, allowing patients to live normal and productive lives. However, the disorder can also be debilitating and, in some cases, life-threatening. NF1 can lead to problems within various systems, organs and functions of the body including:
What is the incidence of neurofibromatosis type 1 (NF1)?
The incidence of NF1 is approximately one in 3,000 live births and it affects males and females of all races equally. Because neurofibromatosis type 1 is hereditary, the risk of developing the features associated with NF1 may be passed from generation to generation in a family.
What are other names for neurofibromatosis?
Medications for Neurofibromatosis. Other names: Bilateral acoustic neurofibromatosis; Central bilateral acoustic NF; Neurofibromatosis 2; Neurofibromatosis-1; NF; NF1; NF2; Von Recklinghausen neurofibromatosis. About Neurofibromatosis: Neurofibromatosis is a genetically-inherited disorder in which the nerve tissue grows tumors.
What is the abbreviation for neurofibromatosis?
What is the abbreviation for Neurofibromatosis? Neurofibromatosis is abbreviated as NFI (also NF, NF-I, Nf, NF1 or NFII)
