Why was zafirlukast discontinued?

Commercial reasons are cited for this decision and it is stressed that there were no safety concerns with this medicine. Zafirlukast is a leukotriene receptor antagonist and as such the closest available alternative is montelukast. Action: Clinicians should be aware of this product being discontinued.

What is the difference between montelukast and zafirlukast?

Singulair (montelukast) Although it’s less effective than inhaled steroid medications for controlling asthma, Accolate (zafirlukast) has less side effects. Makes it easier to breathe. Singulair (montelukast) has fewer side effects but doesn’t work as well as some inhaled medications for asthma and allergies.

Is zafirlukast an inhaler?

Zafirlukast (Accolate) is used to help control the symptoms of asthma and improve lung function. It doesn’t replace your rescue inhaler (albuterol (ProAir, Ventolin, Proventil)) when you’re having an asthma attack, and you need to take it regularly twice a day.

What are the side effects of zafirlukast?

Common side effects may include: nausea, diarrhea, stomach pain; headache; or. cold symptoms such as stuffy nose, sneezing, sore throat.

How does zafirlukast help asthma?

Zafirlukast is used to prevent asthma symptoms. Zafirlukast is in a class of medications called leukotriene receptor antagonists (LTRAs). It works by blocking the action of certain natural substances that cause swelling and tightening of the airways.

Is Accolate and Singulair the same?

Singulair is used to treat asthma and symptoms of allergic rhinitis. Accolate, Zyflo, and Zyflo CR are used to treat asthma. All four drugs are leukotriene inhibitors, which affect the leukotriene pathway, which is involved in the body’s response to inflammatory stimuli (such as breathing in an allergen).

How often do you take zafirlukast?

Zafirlukast comes as a tablet to take by mouth. It is usually taken two times a day, 1 hour before or 2 hours after meals.

Can you take zafirlukast and montelukast together?

Interactions between your drugs Zafirlukast may increase the blood levels and effects of montelukast. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.

What does zafirlukast treat?

Is zafirlukast an anti-inflammatory?

Zafirlukast also exhibited evidence of an anti-inflammatory effect in the lung in preliminary studies involving segmental antigen challenge. The results from these clinical trials demonstrate that zafirlukast is effective and safe for the prophylactic treatment of asthma.

How long does it take for zafirlukast to work?

It may take 1 to 2 weeks before you feel the full benefit of this medication. Inform your doctor if your condition (e.g., asthma symptoms, number of times you use your rescue inhaler) persists or worsens.